Between Failures is a slice-of-life webcomic following the (somewhat under-motivated and decidedly sarcastic) staff of a chain store. The primary protagonist is Thomas Blackwell, but it cuts to follow many members of the staff. It’s often compared to clerks. (It’s actually a lot more like Empire Records, which the author totally suggests you see.) The main focus are the characters and the shenanigans they come up with to keep themselves entertained.

If you've ever had a job where you felt abandoned by the people in charge you'll feel right at home with these people. They're just looking for something meaningful to do in the times between.

The comic doesn't get real heavy, or try to beat you over the head with a message.  It's just the adventures of some fun people.  You might find some wisdom sprinkled in here and there though. 

I also use the comic blog as a journal of my life, and dumping ground for extra thoughts not necessarily related to the comic.  A lot of people seem to enjoy them as much as the comic itself.