Study: protein & seafood. They work!
I liked this study for a couple reasons:

Effect of combined use of a low(ish)-carbohydrate, high-protein diet with omega-3 polyunsaturated fatty acid supplementation on glycemic control in newly diagnosed type 2 diabetes: a randomized, double-blind, parallel-controlled trial (Liu et al., 2018)

There were FOUR groups: 1) high-carb, low protein (HCLP, aka CONtrol group); 2) LCHP; 3) HCLP+n3; and 4) LCHP+n3. So, instead of just taking a group of people, putting them on LCHP+n3 and comparing the results to baseline, they actually controlled for the variables independently.

All groups were assign 30% fat and the protein was either 17% or 28%. THIS WAS CONFIRMED with serum urea nitrogen and you know how much I like biomarkers! n3 status of the n3 groups were confirmed with plasma n3's and you know how much I like biomarkers!

Some more details on the study design...

OK, so it wasn't whole foods PaleoTM. That'd be kind of difficult in a blinded study, so the high protein group got a high protein supplement whereas the low protein group got an identical-tasting low protein supplement. Same went for the n3 supps. I think you'd know you were in the n3 group if they advised 4 servings of salmon per week.

In nearly every endpoint, there was step-wise improvements: Control < HCLP+n3 < LCHP < LCHP+n3. In other words, pretty much exactly what you'd think.

Insulin declined in both LC groups, but this wasn't designed to be a weight loss study (there were no differences in fat mass or body weight).

All-in-all a good study.

Take home: swap out some carbs for some seafood a couple times a week. It works whether you're trying to lose weight or not!

That's all for now :-)

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