Lion's Mane


I'm not taking crazy pills!

Dump various extracts of this stuff on brain cells and they grow.

That's a good sign.

The influence of Lion's Mane on myelination in vitro (Kolotushkina et al., 2003)


Herecinones and erinacines: stimulators of nerve growth factor in Lion's Mane (Ma et al., 2009

and there are any number of animal studies, but we really care about what it can do for us; like, what could we expect from taking this stuff?

We have a couple human studies... 

Improving effects of Lion's Mane on mild cognitive impairment: a double-blind, placebo-controlled clinical trial (Mori et al., 2009)

3 grams/day for 16 weeks. Significant improvement in cognitive function. Not permanent as the effects waned 4 weeks after discontinuing supplementation. In addition to the fact that this was placebo-controlled, in my opinion, that suggests this is clearly not a placebo effect.

Reduction of depression and anxiety with 4 weeks of Lion's Mane supplementation (Nagano et al., 2010)

Significant improvements depression, sleep quality, and quality of life. 

I couldn't find a negative study on Lion's Mane. It was even included in Bredesen's comprehensive program to curb cognitive decline.

For a review: Neurohealth properties of Lion's Mane (Li et al., 2018)

That's all for now!

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