In the final game of the divisional playoffs, the New England Patriots faced the San Diego Chargers, who were unbeaten at home in the regular season. The Chargers' roster included league MVP running back LaDainian Tomlinson, who broke several league records, nine Pro Bowlers, and five All-Pro players. However, four Chargers turnovers, three of which were converted into Patriots scoring drives, helped lead to a Chargers loss. San Diego lost despite outgaining the Patriots in rushing yards, 148–51 and total yards, 352–327, while also intercepting three passes from Tom Brady.
Robbie Gould's 49-yard field goal in overtime propelled the Bears over the Seahawks and to their first NFC Championship Game since the 1988 season. This was also their first playoff win since 1995.